Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09963-3

Different agonists produce equilibria of at least four distinct active states of the G-protein-bound M2 muscarinic acetylcholine receptor, each with a different ability to activate G proteins.

Nature, Published online: 14 January 2026; doi:10.1038/s41586-025-09963-3

Different agonists produce equilibria of at least four distinct active states of the G-protein-bound M2 muscarinic acetylcholine receptor, each with a different ability to activate G proteins.